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Analysis of Specimens From Individuals With Pulmonary Fibrosis
Sponsor: National Human Genome Research Institute (NHGRI)
Summary
The etiology of pulmonary fibrosis is unknown. Analyses of blood, genomic DNA, and specimens procured by bronchoscopy, lung biopsy, lung transplantation, clinically-indicated extra-pulmonary biopsies, or post-mortem examination from individuals with this disorder may contribute to our understanding of the pathogenic mechanisms of pulmonary fibrosis. The purpose of this protocol is to procure and analyze blood, genomic DNA, and specimens by bronchoscopy, lung biopsy, lung transplantation, extra-pulmonary biopsies, or post-mortem examination from subjects with pulmonary fibrosis. In addition, blood, genomic DNA, clinically-indicated extra-pulmonary biopsies, as well as bronchoscopy and post-mortem examination specimens may be procured and analyzed from relatives of subjects with hereditary forms of pulmonary fibrosis; blood, genomic DNA, and bronchoscopy specimens may be procured from healthy research volunteers.
Key Details
Gender
All
Age Range
18 Years - 115 Years
Study Type
OBSERVATIONAL
Enrollment
315
Start Date
2004-06-09
Completion Date
Not specified
Last Updated
2026-04-06
Healthy Volunteers
No
Locations (1)
National Institutes of Health Clinical Center
Bethesda, Maryland, United States