Clinical Research Directory

Inclusion Criteria: * Carcinoma histologically proved and which must be treated by Carboplatin, excepted weekly administered Carboplatin treatments * Age \> 18 years * Neutrophils \> 1500/mm3, blood-platelets \> 100000/mm3 * Patient with intravenous administration route for chemotherapy independent of the one used for blood samples ( for Investigators centers achieving pharmacokinetic examination) * Well-informed written consent, signed by the patient Exclusion Criteria: * Carboplatin treatment's contra-indication * Patient with clinically detectable cerebral metastasis * Pregnant or nursing women * Patient under guardianship or trusteeship * Patient whose venous status don't permit a peripheral intravenous administration route's placing (for Investigators centers achieving pharmacokinetic examination)