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ACTIVE NOT RECRUITING
NCT00169806
NA

Randall's Plaque Study: Pathogenesis and Relationship to Nephrolithiasis

Sponsor: Indiana Kidney Stone Institute

View on ClinicalTrials.gov

Summary

Kidney stones are very common. They affect 3-5% of the population in the United States. Many people are hospitalized for the treatment of kidney stones and some may die. Better understanding of what causes kidney stones is useful in both the treatment and prevention of kidney stones. However, exactly what causes kidney stones is unknown. The most common type of kidney stones contains calcium, which sometimes is attached to a part of the kidney important in producing the final urine, called the papilla. The investigators have noticed that persons who form kidney stones seem to have more papilla with stones attached. They propose to study these areas of the papilla, called Randall's plaques (named after their discoverer), in patients undergoing surgery for kidney stones.

Official title: Randall's Plaques: Pathogenesis and Relationship to Nephrolithiasis

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

600

Start Date

1998-11

Completion Date

2025-12

Last Updated

2025-01-23

Healthy Volunteers

No

Interventions

OTHER

videotape for mapping of renal anatomy and papillary biopsy

Subjects who enroll in this study will have their renal anatomy videotaped for mapping purposes. Stone location and characteristics will be documented as will papilla and calyces. One or more papillary biopsies will be taken for analysis.

Locations (1)

IU Health North Hospital

Indianapolis, Indiana, United States