Clinical Research Directory
Browse clinical research sites, groups, and studies.
A 1-Year Study in Multiple Clinics Testing Rebamipide Eye Drops for Dry Eye Compared With a Placebo
Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Summary
The purpose of this study is to determine the potential safety and effectiveness of rebamipide eye drops, an investigational eye drop being developed for the treatment of keratoconjunctivitis sicca (dry eye).
Official title: Rebamipide Ophthalmic Suspension in the Treatment of Dry Eye: A Multicenter, Phase 3, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, 52 Week Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
755
Start Date
2004-05-01
Completion Date
2007-02-01
Last Updated
2026-06-15
Healthy Volunteers
No
Conditions
Interventions
Rebamipide 1%
ophthalmic suspension
Rebamipide 2%
ophthalmic suspension
Placebo
Rebamipide-matching placebo ophthalmic suspension
Locations (63)
Alabama Research Center, LLC
Birmingham, Alabama, United States
Sun Valley Arthritis Center, Ltd.
Glendale, Arizona, United States
Pivotel Research Center
Peoria, Arizona, United States
Hope research Institute
Phoenix, Arizona, United States
Buena Vista Eye Care Center
Phoenix, Arizona, United States
Radiant Research
Scottsdale, Arizona, United States
Sall Eye Research Center
Artesia, California, United States
Radiant Research - Irvine
Irvine, California, United States
Scripps Clinic Medical Group, Inc.
La Jolla, California, United States
American Eye Institute
Los Angeles, California, United States
Eye Clinic of San Diego
San Diego, California, United States
Healthcare Partners Medical Group
Torrance, California, United States
Centennial Eye Associates
Centennial, Colorado, United States
Corneal Consultants of Colorado
Littleton, Colorado, United States
Western States Clinical Research, Inc.
Wheat Ridge, Colorado, United States
Peter C. Donshik, MDPC
Bloomfield, Connecticut, United States
Opticare Eye Health Center
Waterbury, Connecticut, United States
The Eye Associates
Bradenton, Florida, United States
Hernando Eye Institute
Brooksville, Florida, United States
Radiant Research, Inc. - Lake Worth
Lake Worth, Florida, United States
Suncoast Clinical Research, Inc.
New Port Richey, Florida, United States
Eye Associates International
Ormond Beach, Florida, United States
Pinellas Eye Center
Pinellas Park, Florida, United States
Ft. Lauderdale Eye Institute
Sunrise, Florida, United States
Marvin E. Greenberg, MD PA 7
Tamarac, Florida, United States
Clinical Research of West Florida, Inc.
Tampa, Florida, United States
International Eye Center
Tampa, Florida, United States
Omni Eye Services
Atlanta, Georgia, United States
University of Kentucky, Department of Ophthamology
Lexington, Kentucky, United States
Kentucky Lions Eye Center
Louisville, Kentucky, United States
Gulf Coast Research Associates, Inc.
Baton Rouge, Louisiana, United States
Danial Long, MD
Gretna, Louisiana, United States
Lakeview Optical
New Orleans, Louisiana, United States
Eye Center Northeast
Bangor, Maine, United States
Krieger Eye Institute
Baltimore, Maryland, United States
The Wilmer Eye Institute
Lutherville, Maryland, United States
New England Eye Center
Boston, Massachusetts, United States
The Eye Institute - Lahey Clinic North
Peabody, Massachusetts, United States
Mississippi Eye Associates
Ocean Springs, Mississippi, United States
Montana Medical Research, LLC
Missoula, Montana, United States
Clinical Research Center of Nevada
Las Vegas, Nevada, United States
Eye Associates of New Mexico
Albuquerque, New Mexico, United States
Western New York Eye Center
Orchard Park, New York, United States
Glaucoma Consultants of the Capital Region
Slingerlands, New York, United States
Orellana Retina Associates, PLLC
Raleigh, North Carolina, United States
University Hospitals of Cleveland
Cleveland, Ohio, United States
Comprehensive Opthalmology & Optical Services
Cleveland, Ohio, United States
Clinical Research Source, Inc.
Perrysburg, Ohio, United States
Clinical Research Institute of Southern Oregon
Medford, Oregon, United States
Northwest Corneal Services
Portland, Oregon, United States
Vision Surgery and Laser Center
Roseburg, Oregon, United States
West Hills Vision Center
Moon Township, Pennsylvania, United States
Glaucoma Consultants and Center for Eye Research
Mt. Pleasant, South Carolina, United States
University Eye Surgeons
Maryville, Tennessee, United States
St. Luke's Eye Institute
Amarillo, Texas, United States
Eye Clinic of Austin
Austin, Texas, United States
Baylor College of Medicine
Houston, Texas, United States
Surgical Eye Associates, PA
Houston, Texas, United States
Brazosport Eye Institute
Lake Jackson, Texas, United States
Axia Research
Salt Lake City, Utah, United States
John Moran Eye Center, University of Utah
Salt Lake City, Utah, United States
Physicians Research Options, LC
Sandy City, Utah, United States
Access Eye Research Center
Fredericksburg, Virginia, United States