Clinical Research Directory

Inclusion Criteria: * confirmed HIV-1 infection (ELISA confirmed by Western-Blot test) ; * Age above 18 years * Stable antiretroviral therapy including at least one PI for \>= 3 months, * Plasma HIV-RNA level of \< 50 copies/mL for \>= 3 months before randomization, * Total cholesterol \> = 5.5 mmol/L with LDL-cholesterol \> = 3.4 mmol/L on fasting status after three months of standardized dietary advice, * signed informed consent Exclusion Criteria: * Current AIDS event or infectious disease * Tumoral, inflammatory, muscle diseases; kidney or hepatic failure * Psychiatric conditions * Biological elevated muscular enzymes * Chronic alcohol consumption * Pregnancy