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Detection of Genetic Markers of Lung Cancer
Sponsor: University of Pittsburgh
Summary
The purpose of this research study is to determine the genetic changes and immunologic changes that are involved in the development and progression of bronchogenic lung cancer.
Official title: Detection of Genetic Markers of Lung Cancer Initiation and Progression
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
6000
Start Date
1996-06
Completion Date
2050-12
Last Updated
2025-10-24
Healthy Volunteers
No
Conditions
Interventions
Biopsy of the major carinal area
Biopsy performed intraoperatively
Biopsy of abnormal & suspicious areas of the bronchial tree
Biopsy performed intraoperatively
Evaluation of the tumor for DNA mutations
Tumor tissue is banked for future analysis.
Bronchoalveolar Lavage (BAL) for cytokine analysis
BAL performed intraoperatively
Correlation of flow cytometric & RT PCR for TNM stage
Tissues banked for future correlative studies
Analysis of lymph nodes
Tissues banked for future analysis
Locations (1)
Hillman Cancer Center
Pittsburgh, Pennsylvania, United States