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Identification of Sentinel Lymph Nodes With Methylene Blue and Isotope
Sponsor: University Hospital, Strasbourg, France
Summary
The aim of this study is to evaluate the performance of a double labelling method using isotope and methylene blue dye injection to localize precisely Sentinel Lymph Node (SLN) in a series of 100 patients with infiltrative breast cancer justifying SLN excision. Method and patients: SLN excision will be performed on 100 patients treated for infiltrative breast cancer. After preoperative methylene blue dye injection and lymphoscintigraphy, individual localization of the radioactive and stained nodes will be performed. After the surgery, SLN will be submitted to serial analysis and immunohistochemistry. A comparison of the two methods and an economical evaluation of the complete procedure will be performed.
Official title: Identification of Sentinel Lymph Node (SLN) in Breast Cancer Care: Clinical and Economical Evaluation of a Double Method Using Isotope and Methylene Blue Dye Injection.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2006-04
Completion Date
2008-04
Last Updated
2026-06-08
Healthy Volunteers
No
Conditions
Interventions
Methylene blue (1%)
Rhenium sulfure
Surgical procedure
Anatomo-pathologic procedure
Locations (1)
Service de Gynécologie-Obstétrique, Hôpital Civil
Strasbourg, France