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Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis
Sponsor: University of Pennsylvania
Summary
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare immune system disorder that causes asthma, an excessive number of eosinophils (a type of white blood cell) in the blood, and the inflammation of blood vessels, or vasculitis. In order to properly treat EGPA, it is critical that the level of disease activity can be determined over the course of the disease. The purpose of this study is to determine new biological markers, or biomarkers, that may be used to assess the severity of this disease in people with EGPA.
Official title: Longitudinal Protocol for Eosinophilic Granulomatosis With Polyangiitis
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
700
Start Date
2006-04
Completion Date
2028-12
Last Updated
2026-01-23
Healthy Volunteers
No
Locations (13)
University of California San Diego
San Diego, California, United States
National Jewish Health
Denver, Colorado, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
Mayo Clinic
Rochester, Minnesota, United States
Cleveland Clinic Foundation
Cleveland, Ohio, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
University of Utah
Salt Lake City, Utah, United States
St. Joseph's Healthcare
Hamilton, Ontario, Canada
Mount Sinai Hospital
Toronto, Ontario, Canada
medius KLINIK KIRCHHEIM
Kirchheim unter Teck, Germany
AOU Meyer IRCCS
Florence, Italy
Imperial College Healthcare NHS Trust/ Imperial College London
London, United Kingdom