Clinical Research Directory

Inclusion Criteria: * Males or females 18 years of age or older * Diagnosis of Grade I or Grade II ankle sprain or strain * Meet pain entry criteria * Willing to discontinue use of any pain medication not provided as part of the study Exclusion Criteria: * Have a Grade 3 sprain or Grade 3 strain, bilateral sprain or strain, or concomitant fracture or wound at the site of the sprain or strain. * Have received corticosteroids in the 30 days preceding screening * Have a history or physical examination finding that is incompatible with safe participation in the study * Have a history or physical examination finding that is incompatible with study product use * Are taking medications or other substances contraindicated due to the nature of the study medication or the potential for drug interactions. * Are taking medications that may significantly affect renal function