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Abnormalities of B Lymphocytes During Systemic Lupus
Sponsor: University Hospital, Strasbourg, France
Summary
Previous experimental data strongly suggest that B lymphocytes have intrinsic abnormalities during lupus in mice spontaneously affected by the disease. This study tries to define these abnormalities by looking at the gene expression profile of purified B lymphocytes from patients with non active systemic lupus , compared with the gene expression profile of purified B lymphocytes from healthy donnors.
Official title: Phenotypic Characteristics and Transcriptomas of B Lymphocytes During Non Active Systemic Lupus Erythematosus
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2004-04
Completion Date
2009-05
Last Updated
2026-06-08
Healthy Volunteers
Yes
Conditions
Interventions
Blood samples
Locations (1)
Service d'Immunologie Clinique et VIH - Hôpital Civil
Strasbourg, France