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Impact of Early Parenteral Nutrition Completing Enteral Nutrition in Adult Critically Ill Patients
Sponsor: KU Leuven
Summary
In critically ill patients, a strategy aimed at an early delivery of full caloric support, with a combination of Enteral Nutrition (EN) and Parenteral Nutrition (PN) (in conditions preventing hyperglycemia and overfeeding), results in shorter ICU and hospital stay and less morbidity as compared to a strategy using only EN.
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
4640
Start Date
2007-08
Completion Date
2026-12
Last Updated
2024-02-12
Healthy Volunteers
No
Conditions
Interventions
Withholding PN during the first week of ICU stay
Patients in this arm will receive exclusively enteral nutrition. If enteral nutrition is insufficient after the seventh day of ICU stay, parenteral nutrition will be started.
Oliclinomel N71000 OR N71000E // Clinimix N17G35 OR N17G35E
PN will be started the morning of the third ICU hospitalisation day. The amount of PN to be given will be calculated to cover the caloric needs of the patient, based on the enteral energy intake the previous 24 hours.
Locations (3)
Surgical Intensive Care Unit Regional Hospital Jessa
Hasselt, Belgium
Medical Intensive Care Unit
Leuven, Belgium
Surgical Intensive Care Unit, Catholic University Leuven University Hospitals
Leuven, Belgium