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COMPLETED
NCT00515437
PHASE2

A Multi-Center Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients

Sponsor: Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC

View on ClinicalTrials.gov

Summary

To determine safety, tolerability and preliminary efficacy of intraglandular injections of MYOBLOC for the treatment of sialorrhea in Parkinsons' Disease patients

Official title: A Multi-Center, Randomized, Double-blind, Placebo-Controlled,Sequential Dose Escalation, Safety, Tolerability, and Preliminary Efficacy Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients

Key Details

Gender

All

Age Range

18 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

54

Start Date

2007-07

Completion Date

2008-09

Last Updated

2026-04-21

Healthy Volunteers

No

Conditions

Interventions

BIOLOGICAL

Botulinum Toxin Type B (Myobloc)

BIOLOGICAL

Matched placebo to Myobloc

Locations (18)

Dr Virgilio Evidente

Scottsdale, Arizona, United States

Dr. Ronald Ziman

Northridge, California, United States

Dr. James Sutton

Oxnard, California, United States

Dr. Olga Klepitskaya

Denver, Colorado, United States

Dr. Fernando Pagan

Washington D.C., District of Columbia, United States

Dr Hubert Fernandez

Gainesville, Florida, United States

Dr. Alan Freeman

Atlanta, Georgia, United States

Dr. Katie Kompoliti

Chicago, Illinois, United States

Dr. Robert Rodnitzky

Iowa City, Iowa, United States

Dr. Stephen Reich

Baltimore, Maryland, United States

Dr. Brad Racette

St Louis, Missouri, United States

Dr. Eric Molho

Albany, New York, United States

Dr. Joseph Friedman

Warwick, Rhode Island, United States

Dr. Vanessa Hinson

Charleston, South Carolina, United States

Dr. Sam Kabbani

Knoxville, Tennessee, United States

Dr. Madhavi Thomas

Dallas, Texas, United States

Dr. Gordon Smith

Salt Lake City, Utah, United States

Dr. Patrick Hogan

Tacoma, Washington, United States