Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT00531921

Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

View on ClinicalTrials.gov

Summary

Activity of genes in donor tissues that are involved in inflammation are thought to be involved with early organ dysfunction, increased immune responses in transplant recipients, and organ rejection. The purpose of this study is to determine the relationship between genetic expression in donor and recipient tissue with transplant survival. Participants in this study will have received heart, lung, liver, or kidney transplants.

Official title: Correlation of Donor Proinflammatory mRNA Profiles With Early Outcomes of Thoracic and Abdominal Transplantation

Key Details

Gender

All

Age Range

Any - 70 Years

Study Type

OBSERVATIONAL

Enrollment

313

Start Date

2007-09

Completion Date

2011-08

Last Updated

2026-09-25

Healthy Volunteers

No

Locations (5)

Northwestern Memorial Hospital (kidney and liver)

Chicago, Illinois, United States

Cornell University Medical College (kidney)

Ithaca, New York, United States

Columbia University (lung and liver)

New York, New York, United States

University of Pennsylvania (heart, kidney, liver, lung)

Philadelphia, Pennsylvania, United States

University of Wisconsin (heart and lung)

Madison, Wisconsin, United States