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German Corneal Cross Linking Register
Sponsor: Suphi Taneri
Summary
Corneal Cross Linking is new treatment modality for patients with keratoconus. A keratoconus is characterized by progressive bulging and thinning of the eye's cornea. Keratoconus is a potentially severely sight impairing condition that may necessitate corneal transplantation in the progressive state. Corneal Cross Linking is designed to * increase the cornea's mechanical stability * to stop progression of bulging and thinning of the cornea * to prevent the need for corneal transplantation Corneal Cross Linking is performed by 1. Applying Riboflavin (Vitamin B2) eye drops every 2 minutes for 30 minutes to the cornea 2. Illuminating the cornea with UV-light This register of Corneal Cross Linking procedures performed in Germany serves to * gather long-term results * detect rare complications and side-effects * evaluate the efficacy in a large number of patients
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
7500
Start Date
2007-11
Completion Date
2027-11
Last Updated
2025-01-10
Healthy Volunteers
No
Conditions
Interventions
CCL (Corneal Cross Linking)
Apply Riboflavin 0.1% in Dextran 500 20% in NaCl solution Illuminate with UV-light of 365 nm wave-length and 3.0 mW/cm² intensity at 5 cm distance
Locations (2)
University of Saar
Homburg, Germany
Augenklinik am St. Franziskus Hospital
Münster, Germany