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ACTIVE NOT RECRUITING
NCT00577200
PHASE4

Safety of Driving After Minor Surgery With Monitored Anesthesia Care

Sponsor: Rush University Medical Center

View on ClinicalTrials.gov

Summary

Patients are currently advised to refrain from driving motor vehicles or using public transportation unescorted for a 24 hour period if they undergo any minor ambulatory surgical procedure with monitored anesthesia care (MAC).However, recently introduced short-acting anesthetics may facilitate rapid recovery and an early return to normal daily activities. The proposed study will compare newer short-acting anesthetic agents (propofol, benzodiazepine, opioid) utilized in MAC, to determine if a particular pharmacological agent, or a combination of agents, impair driving performance as evaluated by driving simulator assessment, at time of discharge from the ambulatory center after minor surgical procedures.Subjects will be grouped as patients with chronic pain undergoing procedures and those without chronic pain undergoing procedures. Subjects with pain issues will be randomized with either 1)Midazolam + Sufentanil + Propofol or 2)Midazolam + Sufentanil. There will be a third group of subjects who are controls not undergoing any procedures.

Official title: The Safety of Driving in Patients After Minor Surgery With Monitored Anesthesia Care

Key Details

Gender

All

Age Range

21 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

625

Start Date

2008-01

Completion Date

2026-12

Last Updated

2025-12-16

Healthy Volunteers

Yes

Interventions

DRUG

Midazolam

Midazolam

DRUG

Sufentanil

Sufentanil

DRUG

Propofol

Propofol bolus of 300 µg/kg + infusion at 75 µg/kg/min.

Locations (1)

Rush University Medical Center

Chicago, Illinois, United States