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Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors
Sponsor: Memorial Sloan Kettering Cancer Center
Summary
The purpose of this study is to investigate tumors in the laboratory to determine how and why they respond, or fail to respond to different drug therapies. This study will also investigate why high pressure develops within tumors and how this affects how well drugs work. We will also take blood samples before and/or after your procedure to measure biochemical factors that may help us predict the behavior of osteogenic sarcoma and other solid tumors.
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
763
Start Date
1997-08
Completion Date
2026-08
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Tissue Procurement
MTX polyglutamylation, MTX transport, XTT cytotoxicity assays, Quantitative RT-PCR, Southern blotting, Mutation detection, and Western blotting
Locations (1)
Memorial Sloan Kettering Cancer Center
New York, New York, United States