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Magnetic Resonance Angiography for Peripheral Arterial Disease (PAD)
Sponsor: AMAG Pharmaceuticals, Inc.
Summary
The purpose of this study is to compare the difference between two magnetic resonance imaging (MRI) techniques for visualizing arteries. The study hypothesizes that one method that relies upon imaging flowing blood in the pelvic and leg arteries will not be as accurate or efficient as injecting a safe imaging agent to change the appearance of the blood on the MRI. Both methods will be compared with Digital Subtraction Angiography (DSA).
Official title: Phase II, Open Label, Randomized, Multicenter Trial Comparing Noncontrast MRA vs. Ferumoxytol Vascular Enhanced MRI for Detection of Stenosis or Occlusion of the Aortoiliac and Superficial Femoral Arteries in PAD Subjects Scheduled for DSA
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
119
Start Date
2008-09-01
Completion Date
2020-08-15
Last Updated
2026-04-16
Healthy Volunteers
No
Conditions
Interventions
ferumoxytol
1.0 mg/kg IV ferumoxytol
ferumoxytol
2.5 mg/kg IV ferumoxytol
ferumoxytol
4.0 mg/kg IV ferumoxytol
Locations (1)
Lexington, Massachusetts, United States