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Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Summary
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis. Heart rate fluctuations are highly dependent on ANS control, making the heart one of the best indicators of ANS activity. Low ANS activity level is associated with severe cardiac and cerebral events, as well as to death from any cause in the general population. This PROOF study was hence designed to evaluate ANS activity levels among a healthy retired population, but should these levels decline overtime, to use this as a predictor of cardiovascular and cerebrovascular events, taking into account established cardiovascular risk factors.
Official title: Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events on a Prospective Cohort of Subjects Aged 65 Years
Key Details
Gender
All
Age Range
65 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
1011
Start Date
2000-01-02
Completion Date
2026-12
Last Updated
2025-04-29
Healthy Volunteers
Yes
Conditions
Locations (1)
Centre Hospitalier de Saint-Etienne
Saint-Etienne, France