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Mechanisms Underlying Impaired Diabetic Wound Healing
Sponsor: University of Pittsburgh
Summary
The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.
Key Details
Gender
All
Age Range
21 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2008-09-01
Completion Date
2030-12-31
Last Updated
2025-06-03
Healthy Volunteers
No
Conditions
Interventions
Blood draw
Blood will be drawn from subjects once and VAC sponge will be collected (which is normally discarded material per standard of care).
Locations (5)
Comprehensive Wound Care Centers
Indianapolis, Indiana, United States
Comprehensive Wound Care Centers
Columbus, Ohio, United States
University of Pittsburgh - McKeesport
Pittsburgh, Pennsylvania, United States
University of Pittsburgh - Mercy
Pittsburgh, Pennsylvania, United States
University of Pittsburgh - Passavant
Pittsburgh, Pennsylvania, United States