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An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy
Sponsor: Northwell Health
Summary
The overall goal of this project is to better understand the micro-physiology of human epilepsy and cognition using the intracranial electroencephalogram (iEEG), electrical brain stimulation, functional magnetic resonance imaging (fMRI), and histology.
Official title: An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy Using Electrophysiology, Cortical Mapping, Electrical Brain Stimulation, and fMRI
Key Details
Gender
All
Age Range
5 Years - Any
Study Type
INTERVENTIONAL
Enrollment
450
Start Date
2007-11
Completion Date
2029-02
Last Updated
2024-02-01
Healthy Volunteers
No
Conditions
Interventions
fMRI
Subjects will perform cognitive tasks during MRI scanning sessions to gather data about cognitive functions.
Neuropsychological Testing
Subjects will have a neuropsych evaluation as part of their standard of care for surgery. The research team is asking the subject to release their neuropsychological evaluations for analysis.
Additional electrode implantation
Subjects will typically have between 100-300 electrodes implanted as part of their surgery. Additional electrodes will be implanted that are able to record from smaller, more specific parts of the brain. This will allow for better understanding of how the brain is wired.
Electrical brain stimulation
Intracranial or extracranial electrodes will be used to deliver electrical brain stimulation (amplitude 0.5-8.0mA) or sham stimulation of between 0.4 and 3000 milliseconds during cognitive task periods.
Locations (1)
Comprehensive Epilepsy Care Center
Great Neck, New York, United States