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Radiation Therapy and Docetaxel Followed by Standard Therapy in Treating Women With Breast Cancer
Sponsor: Centre Antoine Lacassagne
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in higher doses over a shorter period of time may kill more tumor cells and have fewer side effects. Drugs used in chemotherapy, such as docetaxel, epirubicin, cyclophosphamide, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) together with radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of radiation therapy when given together with docetaxel followed by standard therapy in treating women with breast cancer.
Official title: Phase I Study - Hypofractionated Cyberknife Radiotherapy Combined With Neoadjuvant Chemotherapy for Breast Tumors
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
26
Start Date
2007-04
Completion Date
2010-12
Last Updated
2026-04-23
Healthy Volunteers
No
Conditions
Interventions
cyclophosphamide
docetaxel
epirubicin hydrochloride
fluorouracil
neoadjuvant therapy
therapeutic conventional surgery
hypofractionated radiation therapy
image-guided radiation therapy
radiation therapy
stereotactic radiosurgery
Locations (1)
Centre Antoine Lacassagne
Nice, France