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Epidural Study of Patients With Chronic Lower Back Pain
Sponsor: McMaster University
Summary
The purpose of this study is to examine 4 different epidural dosing regimes of local anaesthetic solution in a series of 3 epidural injections over a period of 12 months to determine the optimum dose of anaesthetic solution for pain relief and to determine the nature of any adverse events by measuring anxiety and depression, functionality and any side effects of the medication.
Official title: Effects of Volume and Dose of Local Anaesthetic Solution in Epidural Steroidal Injections for Patients With Chronic Lower Back Pain
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
252
Start Date
2005-05
Completion Date
2011-09
Last Updated
2026-06-10
Healthy Volunteers
No
Conditions
Interventions
Bupivacaine
Low Volume, Low Dose (5cc, 5mg plain Bupivacaine)
Bupivacaine
Low Volume, High Dose (5cc, 10mg plain Bupivacaine)
Bupivacaine
High Volume, Low Dose (10cc, 5mg plain Bupivacaine)
Bupivacaine
High Volume, High Dose (10cc, 10mg plain Bupivacaine)
Depo-Medrol
80mg Depo-Medrol
Locations (1)
Hamilton General Hospital
Hamilton, Ontario, Canada