Clinical Research Directory
Browse clinical research sites, groups, and studies.
Morphine COnsumption in Joint Replacement Patients, With and Without GaBapentin Treatment, a RandomIzed ControlLEd Study
Sponsor: McMaster University
Summary
Total hip arthroplasty is amongst the most painful procedures postoperatively, and pain management can be a challenge. Different measures have been introduced to manage severe postoperative pain in these patients. Previous studies have investigated gabapentin in acute postoperative pain and demonstrated reduced postoperative pain, postoperative morphine consumption, morphine related side effects, and postoperative pain scores. To date, this analgesia adjunct has yet to be investigated for total joint arthroplasty patients.
Official title: Multiple Doses of Gabapentin and Postoperative Morphine Consumption in Primary Hip Arthroplasty
Key Details
Gender
All
Age Range
19 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
103
Start Date
2007-10
Completion Date
2011-02
Last Updated
2026-06-08
Healthy Volunteers
No
Conditions
Interventions
Gabapentin
600mg gabapentin given 2 hrs preoperatively and 200mg three times a day after surgery for 3 days
Placebo
Half the patients will be randomized to placebo
Locations (1)
Hamilton Health Sciences
Hamilton, Ontario, Canada