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Determinants of Cognitive Impairment After Acute Coronary Syndrome
Sponsor: University Hospital, Bordeaux
Summary
The general purpose of the present pathophysiological study is to investigate the relation between cognitive impairment observed after an acute coronary syndrome and the presence of cerebral anatomo-functional abnormalities. This study will improve the investigators' understanding of the disease and will help in early diagnosis and prevention of vascular dementia in this population.
Official title: Anatomo-functional Determinants of Cognitive Impairment After Acute Coronary Syndrome: A Brain MRI and Cerebral Perfusion Scintigraphy Study
Key Details
Gender
All
Age Range
35 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
49
Start Date
2009-09
Completion Date
2013-05
Last Updated
2026-06-09
Healthy Volunteers
No
Conditions
Interventions
Brain MRI and cerebral perfusion scintigraphy
A standard neuropsychological assessment will be performed by a neuropsychologist. The daily life experience study will be performed. Questions will be asked to the patients by a pocket computer (Palm). MRI will be performed on a 3 Tesla research MRI. Two Tc-99m-HMPAO SPECT studies will be performed The second SPECT study will be performed after intravenous injection of acetazolamide.
Locations (2)
CHU de Bordeaux
Bordeaux, France
Hôpital Cardiologique du Haut-Lévêque (CEPTA)
Pessac, France