Clinical Research Directory

Inclusion Criteria: * All patients included must meet one of these two conditions: * Patient presenting with an episode of transient ischemic attack (TIA) of cryptogenic origin with neurological symptoms of less than 24h of evolution and negative neuroimaging. * First episode of ischaemic stroke with cryptogenic etiology following TOAST criteria * All patients must meet all of the following: * The patient has been implanted an ILR within 30 days after qualifying event * Age between 45-85 years * No stenosis \>50% in any arterial vessel corresponding to the affected territory * Normal Echocardiography * Normal 24 hours EKG Holter recording * Absence of Patent Foramen Ovale through transcranial doppler (or transesophageal echocardiography) * Acceptance and signature of Patient Informed Consent. Exclusion Criteria: * All patients included cannot meet any of the following conditions: * Recurrent stroke or TIA * Stroke or TIA with determined etiology according to TOAST criteria. * Anticoagulation indication at the time of enrollment in the study. * Total contraindication for anticoagulation therapy * Atrial fibrillation detection prior to enrollment * Severe cognitive impairment or dementia * Patient unable to be followed up * Patients enrolled in another clinical trial * Patients with life expectancy of less than 1 year * Pregnancy