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Emergency Preservation and Resuscitation (EPR) for Cardiac Arrest From Trauma
Sponsor: University of Maryland, Baltimore
Summary
The goal of this study is to rapidly cool trauma victims who have suffered cardiac arrest from bleeding with a flush of ice-cold sodium chloride to preserve the patient to enable surgical control of bleeding, followed by delayed resuscitation with cardiopulmonary bypass.
Official title: Emergency Preservation and Resuscitation for Cardiac Arrest From Trauma
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2016-10
Completion Date
2025-11-21
Last Updated
2026-06-16
Healthy Volunteers
No
Conditions
Interventions
Emergency preservation and resuscitation
This involves the induction of profound hypothermia using a flush of ice-cold saline into the aorta. Once hypothermia is achieved, the subject would undergo rapid operative interventions to control bleeding followed by resuscitation/rewarming with cardiopulmonary bypass.
Standard resuscitation
Standard resuscitation includes an emergency department thoracotomy, open cardiac massage, and fluid resuscitation.
Locations (1)
University of Maryland
Baltimore, Maryland, United States