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Pharmacogenomics ANDA SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms
Sponsor: Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair
Summary
Explore the relationship between drug target topoisomerase II gene single nucleotide polymorphisms and Etoposide (VP-16) therapeutic-effects in patients with small cell lung cancer, based on Oxford precisely sequencing drug targets' genes. Explore the relationship between drug target CYP4503A4 gene single nucleotide polymorphisms and Etoposide (VP-16) side-effects in patients with small cell lung cancer, based on Oxford precisely sequencing drug targets' genes.
Official title: Explore the Relationship Between Single Nucleotide Polymorphisms and Etoposide Response and Toxicity in Patients With Small Cell Lung Cancer.
Key Details
Gender
All
Age Range
24 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
600
Start Date
2025-07-16
Completion Date
2026-12-28
Last Updated
2025-07-24
Healthy Volunteers
No
Conditions
Interventions
ETOPOSIDE - Usual
Etoposide Capsule
ETOPOSIDE - Study
China Import Etoposide Capsule
Locations (1)
Medicine Invention Design, Inc. (MIDI) - IORG0007849 - NPI 1023387701
Rockville, Maryland, United States