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Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Sponsor: Centre Hospitalier Universitaire de Nice
Summary
Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years. At present time,there is no effective treatment against digital arthritis. The investigators purpose to measure the efficacy of methotrexate on digital arthritis. In this aim, two groups were compared. The first group receive 10mg/week of methotrexate administered in one shot (every Monday for example)during 12 months. The second group receive 10mg/week of placebo according to the same procedure
Official title: Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo - Assessment of Structural and Clinical Action of Magnetic Resonance Imaging
Key Details
Gender
All
Age Range
40 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2010-05-25
Completion Date
2018-10-15
Last Updated
2026-06-17
Healthy Volunteers
No
Conditions
Interventions
Methotrexate
Methotrexate: 10mg/week administered in one time, the same day each week (every monday for example)during 12 months
Placebo
Placebo:10mg/week administered in one time, the same day each week (every monday for example)during 12 months
Locations (1)
Nice University Hospital, Rheumatology Department
Nice, France