Clinical Research Directory
Browse clinical research sites, groups, and studies.
A European Network for the Investigation of Gender Incongruence
Sponsor: University Hospital, Ghent
Summary
The physical and psychological effects of the hormonal treatment of transsexual persons are not sufficiently described. 'Transparency' wants to answer this question in a prospective manner, in a multicenter study to describe these effects. The low prevalence of transsexualism was the stimulus to search for European partners for this Protocol. A common standardized hormonal protocol was designed.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
125
Start Date
2010-02-15
Completion Date
2030-12-31
Last Updated
2023-12-11
Healthy Volunteers
No
Interventions
questionnaires
a descriptive questionnaire, SF-36, , bone questionnaires, Baecke physical activity questionnaire, voice evaluation
blood sampling
LFT (AST, ALT), CRP, creatinine, glucose, Total Cholesterol, Triglycerides, HDL-CH, LDL-CH, 25OH vitamin D, PSA if\> 45 years, Hematocrit, testosterone, sex hormone-binding globulin, free testosterone , oestradiol, prolactin, luteinizing hormone, TSH, androgeengevoeligheids test (CAG RL), oral glucose tolerance test
clinical evaluation
height, weight, blood pressure, chestcircumference, waist circumference, grip strength, measuring 2 ° and 4 ° finger, and Ferriman Gallwey score
Dermatology evaluation
Evaluation of the hair pattern, using the Leeds acne classification scale, acne scars through ECCA scale (échelle d'évaluation clinique des cicatrices d'acné), androgenetic alopecia, and sebummetrie
Bone evaluation
PQCT scanner, BMD assessment
Locations (4)
Genderteam UZ Gent
Ghent, Belgium
Florence, Italy
VU University Medical CenterAmsterdam
Amsterdam, Netherlands
Rikshospitalet University Hospital, University of Oslo
Oslo, Norway