Clinical Research Directory
Browse clinical research sites, groups, and studies.
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
Sponsor: University of Utah
Summary
Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.
Official title: Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease, Effects of Mechanical Unloading on Myocardial Function and Structure in Humans
Key Details
Gender
All
Age Range
13 Years - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2008-09
Completion Date
2028-01
Last Updated
2025-07-15
Healthy Volunteers
No
Conditions
Locations (3)
Intermountain Medical Center
Murray, Utah, United States
University of Utah Health Sciences Center
Salt Lake City, Utah, United States
VA Salt Lake City Health Care System
Salt Lake City, Utah, United States