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RECRUITING
NCT01099982

Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease

Sponsor: University of Utah

View on ClinicalTrials.gov

Summary

Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.

Official title: Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease, Effects of Mechanical Unloading on Myocardial Function and Structure in Humans

Key Details

Gender

All

Age Range

13 Years - Any

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2008-09

Completion Date

2028-01

Last Updated

2025-07-15

Healthy Volunteers

No

Locations (3)

Intermountain Medical Center

Murray, Utah, United States

University of Utah Health Sciences Center

Salt Lake City, Utah, United States

VA Salt Lake City Health Care System

Salt Lake City, Utah, United States