Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT01115387

GARM II: A Study on the Genetics of Age-related Maculopathy

Sponsor: University of California, Los Angeles

View on ClinicalTrials.gov

Summary

The original study (GARM I) has been conducted for more than 18 years at the University of Pittsburgh Medical Center (UPMC). GARM II is a nationwide research study about age-related macular degeneration in the next generation of adults (49 to 65 years old). The purpose of this study is to identify the hereditary and exposure risk factors that lead to the development of ARM (Age related maculopathy). Participants will communicate with the research staff through a protected and confidential website and use this website to complete a number of questionnaires during the course of the study (see below). For genetic analyses, the participants will mail in easily self-collected saliva samples in special containers. Eye photographs and eye health records are sent to the research center from local sources through the Internet. Individuals are not expected to come to UCLA in order to participate. https://jseiclinres.jsei.ucla.edu/garm/ Participants will be expected to answer questionnaires or surveys about medical history, ocular history and visual symptoms, family history, smoking, dietary supplements and light exposure.

Official title: Genetics of Age Related Maculopathy

Key Details

Gender

All

Age Range

49 Years - Any

Study Type

OBSERVATIONAL

Enrollment

603

Start Date

2011-10-06

Completion Date

2027-03

Last Updated

2023-11-07

Healthy Volunteers

Yes

Interventions

OTHER

Observational-1

Multiple questionnaires detailing family history, medical history, visual symptoms, smoking, environmental and dietary exposures. Prospective photography of the retina to detect early ARM-related changes A saliva or blood sample for genetic testing.

OTHER

Observational-2

A limited number of questionnaires and prior clinical documentation from eye care professionals of eye status with respect to ARM. No prospective retina photographs but ongoing follow-up for reported changes in ARM status. A saliva or blood sample for genetic testing.

Locations (2)

Jules Stein Eye Institute, Dept. of Ophthalmology David Geffen School of Medicine at UCLA

Los Angeles, California, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States