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Plasm Gastrin Concentrations in Response to Nexium Administration in Healthy Volunteers
Sponsor: City of Hope Medical Center
Summary
This dose response study is proposed to explore the extent to which Nexium increases endogenous gastrin concentrations and to assess whether Nexium treatment may be useful in the setting of islet cell transplantation for type 1 diabetes to expand islet cells in vivo after transplant.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2010-07-13
Completion Date
2012-04-01
Last Updated
2026-10-19
Healthy Volunteers
Yes
Conditions
Interventions
Esomeprazole Magnesium
NEXIUM 40MG ONCE DAILY FOR 7 DAYS WITH A 2 WEEK WASHOUT PERIOD, NEXIUM 40MG TWICE DAILY WITH A 2 WEEK WASHOUT PERIOD, NEXIUM 80MG TWICE DAILY WITH A 2 WEEK WASHOUT PERIOD.
Locations (1)
City of Hope Medical Center
Duarte, California, United States