Clinical Research Directory

Inclusion Criteria: * Male or Female between 5 and 17 years of age at enrollment * An efficient contraceptive method for girls with childbearing potential. Acceptable methods include sexual abstinence, oral, injectable contraceptive methods, intra uterine device. * Negative pregnancy test for girls with childbearing potential. * Child with a documented allergy to peanut, i.e. with peanut-specific IgE (\>5KU/L, ImmunoCAP method) and/or a positive skin prick test to peanut (wheal diameter ≥ 8mm). * Child able to consume a cumulated quantity of peanut proteins \<250 mg during the baseline DBPCFC. * Child and his/her legal representative(s) who provide a signed consent form and assent form. * Child and his/her legal representative(s) whose family and social conditions allow them to understand the protocol and agree to comply in the long term with all study requirements. Exclusion criteria : * Child considered too severely allergic to peanut: with a history of severe anaphylaxis to peanut (with hypotension, loss of consciousness, severe bradycardia, respiratory or cardiac arrest requiring an admission to emergency rooms). * Child with peanut-specific IgE\<5 KU/L and whose skin prick test to peanut gave a wheal diameter \<8mm). * Child participating or having participated in a therapeutic study in the last 3 months * Pregnancy or Breastfeeding * Child with a generalized eczema * Child with an immune deficiency * Diabetic child * Child allergic to chocolate * Child or legal representative(s) who did not sign their consent or assent * Child with no baseline DBPCFC * Child having reacted to placebo during the baseline DBPCFC * Child able to consume \> 250 mg of cumulated peanut proteins during the baseline DBPCFC * Child with a respiratory deficiency or with an uncontrolled asthma. * Child who could not discontinue oral or I.V. antihistamines or oral or I.V. corticosteroids at least the week prior to Visit 1. * Child with important skin lesions precluding the application of the disks. * Child not affiliated to social security.