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Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Sponsor: Copenhagen Studies on Asthma in Childhood
Summary
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence of clear clinical bacterial infection which would in any case precipitate antibiotic treatment - has an effect on either the particular episode, or subsequently. Macrolide antibiotics are chosen for ease of administration ensuring high compliance, antibiotic appropriacy, and anti-inflammatory properties.
Official title: Antibiotic Treatment of Recurrent Episode of Asthma in Children - a Randomised, Case-controlled Study Within the COPSAC2010 Cohort (Asthma Begins in Childhood)
Key Details
Gender
All
Age Range
1 Year - 3 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2010-11
Completion Date
2033-10
Last Updated
2026-03-18
Healthy Volunteers
No
Conditions
Interventions
Azithromycin
10 mg/kg peroral for 3 consecutive days
Placebo mixture
Placebo mixture containing no active substance.
Locations (2)
Copsac, DBAC
Gentofte Municipality, Copenhagen, Denmark
Copsac, Næstved Hospital, Pediatric Department
Næstved, Denmark