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Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery
Sponsor: M.D. Anderson Cancer Center
Summary
This clinical trial studies wide-field and high resolution in vivo imaging in visualizing lesions in patients with abnormal or uncontrolled oral cell growth (neoplasia) undergoing surgery. Diagnostic procedures, such as wide-field and high resolution in vivo imaging, are devices that let researchers look at a wide area of the lining of the mouth by shining different colors inside the mouth and taking pictures and this may help doctors to decide if a mouth lesion has a high risk of being pre-cancerous or cancerous.
Official title: Wide-Field and High Resolution In Vivo Imaging of Oral Neoplasia Using Topical Fluorescent Dyes: A Feasibility Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
275
Start Date
2010-12-30
Completion Date
2028-12-31
Last Updated
2026-02-11
Healthy Volunteers
No
Conditions
Interventions
High-Resolution Microendoscopy
Undergo evaluation of oral lesions using a high-resolution microendoscope
Multispectral Imaging
Undergo evaluation of oral cavity using a widefield multispectral imaging
Proflavine
Proflavine) used to stain the mouth tissue after initial imaging.
Locations (1)
M D Anderson Cancer Center
Houston, Texas, United States