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Effects of a Long-term Grapefruit Juice Consumption on Vascular Protection and Bone Metabolism
Sponsor: University Hospital, Clermont-Ferrand
Summary
Epidemiological studies definitively show that fruit and vegetable consumption is an important factor for the prevention of age-related diseases such as cardiovascular diseases (CVD) and osteoporosis. Citrus fruits are among the fruits which are the most frequently consumed worldwide, essentially as juices. Citrus fruits are the exclusive sources of a particular class of dietary flavonoids, namely flavanones. Grapefruit consumed as whole fruit or juice corresponds to a quantitatively significant source of a specific flavanone called naringin.
Official title: Effects of a Long-term and Regular Grapefruit Juice Consumption on Vascular Protection and Bone Metabolism : a Cross-over Designed Study to Determine the Specific Role of Naringin
Key Details
Gender
FEMALE
Age Range
50 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2010-03
Completion Date
2011-12
Last Updated
2026-07-31
Healthy Volunteers
Yes
Conditions
Interventions
Long-term grapefruit juice consumption
The main goals of this project are (1) to characterize the effect of a long-term grapefruit juice consumption on both vascular and bone protections and (2) to assess the specific role of naringin, in these potential protective effects.
Locations (1)
CHU Clermont-Ferrand
Clermont-Ferrand, France