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Oscillatory Versus Non-Oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support
Sponsor: University of Utah
Summary
This study will seek to enroll neonates requiring Nasal Continuous Airway Pressure (NCPAP) respiratory support and randomize them to either oscillatory (Osc-NCPAP, study group) or non-oscillatory (NCPAP, control group) mode. The goal of the research is to determine if Osc-NCPAP provides improved ventilation support compared to routine NCPAP, i.e. NCPAP without oscillations. This will be measured by need for change to ventilator support, improvement in pCO2 values, and reduction in respiratory rate and frequency of apnea during the period of NCPAP treatment. Other respiratory outcomes will also be compared, including time on NCPAP, time on High-Flow Nasal Cannula support following NCPAP, and time-averaged PiO2 from start of study to end of respiratory treatment.
Key Details
Gender
All
Age Range
Any - 28 Days
Study Type
INTERVENTIONAL
Enrollment
0
Start Date
2014-12
Completion Date
2017-04
Last Updated
2026-08-13
Healthy Volunteers
No
Conditions
Interventions
Nasal CPAP
NCPAP is delivered via nasal prongs placed into infant's nares. It may be delivered via ventilator or by bubble.
Oscillatory NCPAP
Bird Industries pneumatic diaphragm is attached to NCPAP patient circuit to provide oscillations.
Locations (3)
Valley Children's Healthcare
Madera, California, United States
Primary Children's Medical Center
Salt Lake City, Utah, United States
University of Utah Health Sciences Center
Salt Lake City, Utah, United States