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Study of Changes in Estrogen Levels and Grip Strength in Postmenopausal Women Who Have Received 4 to 6 Years of Hormone Therapy for Breast Cancer and Are Currently Receiving Letrozole on Clinical Trial IBCSG-35-07
Sponsor: ETOP IBCSG Partners Foundation
Summary
RATIONALE: Studying samples of blood in the laboratory from patients receiving treatment for cancer may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer. PURPOSE: This clinical trial is studying changes in estrogen levels and grip strength in postmenopausal women who have received 4 to 6 years of hormone therapy for breast cancer and are currently receiving letrozole on clinical trial IBCSG-35-07.
Official title: SOLE Estrogen Substudy (SOLE-EST) - Investigating Changes in Estrogen Levels and Grip Strength for Patients Participating in the SOLE Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 120 Years
Study Type
OBSERVATIONAL
Enrollment
104
Start Date
2011-01
Completion Date
2019-05-15
Last Updated
2026-10-06
Healthy Volunteers
No
Conditions
Interventions
polymorphism analysis
SNPs will be genotyped in whole blood samples taken at baseline.
laboratory biomarker analysis
Biomarkers will be assessed in blood and serum samples at different time points.
quality-of-life assessment
Quality of life will be assessed using the Breast Cancer Prevention Trial (BCPT) Symptom Scales and the IBCSG Trial 35-07 QL Form.
Locations (2)
Box Hill Hospital
Box Hill, Victoria, Australia
CHU Liege - Domaine Universitaire du Sart Tilman
Liège, Belgium