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Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Summary
There is a need to develop blood and/or urine tests that will help to detect early signs of rejection in people who have had kidney transplant. Researchers will examine blood, urine, and tissue samples and try to identify genetic markers for certain conditions like rejection, response to therapy, and scarring of the kidney. By studying gene patterns, researchers hope to be able to diagnose these conditions earlier and improve kidney survival.
Official title: Discovery and Validation of Proteogenomic Biomarker Panels in a Prospective Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients - Transplant Proteogenomics
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
307
Start Date
2011-03
Completion Date
2016-06
Last Updated
2026-09-25
Healthy Volunteers
No
Conditions
Locations (5)
Mayo Clinic, Division of Nephrology
Phoenix, Arizona, United States
The Scripps Research Institute, Scripps Center for Organ and Cell Transplantation,
La Jolla, California, United States
Northwestern University, Feinberg School of Medicine, Division of Organ Transplantation
Chicago, Illinois, United States
The Cleveland Clinic
Cleveland, Ohio, United States
Medical University of South Carolina, Division of Transplant
Charleston, South Carolina, United States