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Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment
Sponsor: McMaster University
Summary
Total knee arthroplasty is amongst the most painful procedures postoperatively, and pain management can be a challenge. Different measures have been introduced to manage severe postoperative pain int hese patients. Previous studies have investigated gabapentin in acute postoperative pain and demonstrated reducted pain, postoperative morphine consumption, morphine related side effects, and postoperative pain scores. To date, this analgesia adjunct has yet to be investigated in total joint arthroplasty patients.
Official title: Multiple Doses of Gabapentin and Postoperative Morphine Consumption in Total Knee Arthroplasty
Key Details
Gender
All
Age Range
19 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
101
Start Date
2007-10
Completion Date
2011-02
Last Updated
2026-06-10
Healthy Volunteers
No
Interventions
Gabapentin
600mg of Gabapentin will be given orally preoperatively and 200mg for 3 times a day after surgery for 3 days
Placebo
Placebo will match the the gabapentin pill and will be given orally.
Locations (1)
Hamilton Health Sciences
Hamilton, Ontario, Canada