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Copeptin and Acute Coronary Syndrome Without ST-segment Elevation
Sponsor: University Hospital, Clermont-Ferrand
Summary
The purpose of this study is to determine whether the combination of copeptine and troponin adds diagnosis information to that provided by troponin alone or the combination of troponin and myoglobin. Hypothesis : If the values of troponin and copeptin are not elevated, diagnosis of acute myocardial infarction can be ruled out without prolonged monitoring and serial blood sampling.
Official title: Diagnostic Value of Copeptin Assay for Acute Coronary Syndrome Without ST-segment Elevation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
134
Start Date
2011-03
Completion Date
2012-03
Last Updated
2026-08-06
Healthy Volunteers
No
Conditions
Interventions
Copeptin
Patients with hyponatremia \< 135 mmol/L or troponin \> 1 μg/L are released study. Blood sampling are taken for Troponine T, myoglobin, creatin kinase and copeptine analysis and 18-lead ECG was performed after 2, 4, 6 and 12 h. Copeptin and myoglobin are measured at the end of the patients inclusion, after to be centrifugrd end frozen at -80°C at each time point. The treatment of patients is not modified by the study. At 90 days, clinicals and paraclinicals events are collected
Locations (1)
CHU Clermont-Ferrand
Clermont-Ferrand, France