Clinical Research Directory

Inclusion Criteria: * Patients aged between 18 and 65 years old. * Body mass index lower than 35 * Degenerative osteoarthritis painful and invalidating degenerative lumbar vertebra for at least 6 months and resistance fighter in the conservative treatment * Narrow lumbar canal and\\or spondylolisthesis with neurological disorder associated with signs of primary instability or induced to neurological liberation * Patient requiring a surgery on a single interbody level. * Given informed consent * Patient with French health system Exclusion Criteria: * For women: no efficient contraception (intra uterine device, or contraceptive pill) * Pregnant or feeding women * Surgery zone local infection local * Lumbar interbody fusion of more than two levels * Spondylolisthesis of high rank (stage 3 or 4 of the classification of Meyerding) * Scoliosis lumbar vertebra gives a complex to (Cobb angle\> 40°) * All surgical contraindications * Severe hyperparathyroidism: calcium \> 2,45 mmol/l and \[PTH\] ≥ 50pg / ml * Uncontrolled diabetes (untreated or non stabilized by treatment) * Long corticoid treatment (more than 6 months and stopped since less than 3 months) * Current Chemotherapy or during the last three months * Antecedent of regional radiotherapy * All contraindication to MatriTM BONE: osteomyelitis, bone degenerative disease or necrosis of surgery site. * Known turned out Osteoporosis untreated (dexa: \> 2 DS) * Subject participating in another research including a period of always current exclusion in the pre-inclusion * Person placed under protection of justice * Severely altered physical and\\or psychological Health, which according to, the investigator, can affect to participant's compliance to the study.