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Genes and Environment in Multiple Sclerosis
Sponsor: Columbia University
Summary
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS will be beneficial in the future if the investigators can identify effective ways to prevent or slow down the progression of this disease.
Official title: Integrating Genetic and Environmental Risk Scores Into an Algorithm to Predict Multiple Sclerosis Susceptibility
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
5000
Start Date
2017-10-01
Completion Date
2040-10
Last Updated
2025-04-24
Healthy Volunteers
Yes
Conditions
Locations (5)
National Institute of Neurological Disorders and Stroke
Bethesda, Maryland, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
Columbia University Irving Center
New York, New York, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, United States