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Prevention of West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH)
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
Summary
West syndrome (WS) is a specific type of epilepsy (or seizure disorder) that has three features: infantile spasms (type of seizure), loss of milestones, and a specific pattern on electroencephalogram (EEG or brain wave test) called hypsarhythmia. The purpose of this study is to detect pre-hypsarhythmia in infants at high-risk for WS and determine whether treatment with ACTH will prevent WS.
Official title: Early Treatment of Infants at High Risk of Developing West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH)
Key Details
Gender
All
Age Range
2 Months - 12 Months
Study Type
INTERVENTIONAL
Enrollment
6
Start Date
2011-07
Completion Date
2020-05-05
Last Updated
2026-08-14
Healthy Volunteers
No
Conditions
Interventions
adrenocorticotropin hormone
ACTH 16 units intramuscular injection once daily for 2 weeks
Locations (1)
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, United States