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Inflammatory Response Following Intraarticular Fracture
Sponsor: University of Utah
Summary
The purpose of the study is to investigate a relationship between the inflammatory response following intraarticular fracture and post-traumatic osteoarthritis. The investigators plan to evaluate the inflammatory cytokine profile in knee joint synovial fluid and blood serum in patients who sustain an intraarticular tibial plateau fracture and ankle joint synovial fluid and blood serum in patients who sustain an intraarticular tibial plafond fracture. This information will be combined with radiographs and patient outcome measures to determine a correlation between intraarticular inflammatory response and post-traumatic osteoarthritis.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2011-10
Completion Date
2026-12
Last Updated
2025-08-12
Healthy Volunteers
No
Locations (1)
University of Utah Orthopedics
Salt Lake City, Utah, United States