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Associating Renal Transplantation With the ITN Signature of Tolerance
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Summary
This is an observational study for people who have received a kidney transplant within the past 1 to 5 years. Researchers in this study are looking for a certain pattern of genes and cells in the blood that has been found in a group of rare transplant patients who do not need immunosuppression. The study goal is to find out how common this pattern is in transplant patients, as a first step in determining if it can be used to personalize anti-rejection drug regimens better.
Official title: An Observational Study to Assess the Prevalence of a Tolerance Signature in Renal Transplant Recipients (ITN524ST/CTOT-12)
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2010-09
Completion Date
2014-04
Last Updated
2026-09-25
Healthy Volunteers
No
Conditions
Locations (8)
University of Alabama Birmingham
Birmingham, Alabama, United States
University of California San Francisco
San Francisco, California, United States
Emory University
Atlanta, Georgia, United States
Northwestern University
Chicago, Illinois, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
Mount Sinai School of Medicine
New York, New York, United States
The Cleveland Clinic Foundation
Cleveland, Ohio, United States