Clinical Research Directory

Inclusion Criteria: * Are 12 to 59 months of age. * Have received a solid organ transplantation requiring ongoing immunosuppression. * Have been receiving immunosuppressive agents for at least 3 months. Non-steroidal anti-inflammatory agents, G-CSF, erythropoietin and inhaled corticosteroids are not considered immunosuppressive agents for the purposes of this study. * Expect to be able to complete the study injection and follow-up. * Have parent or guardian's consent. * Have received at least 3 doses of an approved PCV7 and/or PCV13 vaccine series. Exclusion Criteria: * Have received any inactivated vaccine within 4 weeks, or any live vaccine within 6 weeks of entering the study. * Have had an allergic reaction or a serious side effect after receipt of any previous immunization to pneumococcal vaccines, or to other routine childhood immunizations. * Have any other condition that would make receiving study vaccine inadvisable. * Have other diseases of the immune system. * Have any other disease or previous surgery that would interfere with study treatment. * Are likely to have bleeding disorders.