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ACTIVE NOT RECRUITING
NCT01529983
EARLY_PHASE1

Fractional Laser vs. Ultrasound for Periorbital Wrinkles

Sponsor: Northwestern University

View on ClinicalTrials.gov

Summary

The primary objective of this study is to compare the efficacy of intense focused ultrasound and carbon dioxide-fractionated laser for treatment of periorbital wrinkles.

Official title: A Comparison of 1550-nm Fractional Photothermolysis Versus Intense Focused Ultrasound for Treatment of Periorbital Wrinkles: A Pilot, Prospective Randomized Control Trial

Key Details

Gender

All

Age Range

35 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2012-02

Completion Date

2025-12

Last Updated

2025-01-31

Healthy Volunteers

Yes

Conditions

Interventions

PROCEDURE

Laser treatment

The treated sites are both lower eyelids and lateral orbits. Each side will be randomized to receive 1550nm-fractionated laser treatment on one side and the contralateral side will receive micro-focused ultrasound treatment every 6-8 weeks for a total of 2 treatments

DEVICE

High-intensity focused ultrasound

High-intensity focused ultrasound (HIFUS) is an FDA-approved method for periorbital treatment and nonablative tissue tightening. Ultrasound waves induce a vibration in the tissue, generating heat and increasing the tissue temperature within a focal area. The tissue changes depend on amount of heat and exposure duration. These findings are similar to the thermally induced changes within the skin after CO2 laser fractional ablative treatments.

Locations (1)

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, Illinois, United States