Clinical Research Directory

Inclusion Criteria: * Painful and disabled knee joint resulting from osteoarthritis, rheumatoid arthritis, traumatic arthritis where one or more compartments are involved. * Correction of varus, valgus or post-traumatic deformity * Correction or revision of unsuccessful osteotomy, arthrodesis, or failure of previous joint replacement procedure * Ability and willingness of the patient to attend follow-up visit. * Willing to give written informed consent * Patients are at least 18 years of age, no upper age limit, must have reached full skeletal maturity. Exclusion Criteria: * infection * sepsis * osteomyelitis Relative Contraindications: * An uncooperative patient or a patient with neurologic disorders who is incapable of following directions * Osteoporosis * Metabolic disorders which may impair brain function * Osteomalacia * Distant foci of infections which may spread to the implant site * Rapid joint destruction, marked bone loss, or bone resorption apparent on roentgenogram * Vascular insufficiency, muscular atrophy, neuromuscular disease * Incomplete or deficient soft tissue surrounding the knee Additional research-related exclusion criteria: patients who have a history of or current infection in the affected knee.