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Radical Fimbriectomy for Young BRCA Mutation Carriers
Sponsor: Centre Oscar Lambret
Summary
Some BRCA-mutated women are reluctant to undergo laparoscopic bilateral salpingo-oophorectomy. The goal of the bilateral laparoscopic radical fimbriectomy the investigators suggest, is to suppress the tubal source of possible dysplastic cells from which can stem this high grade tumor, while preserving a natural ovarian hormonal secretion.
Official title: Radical Fimbriectomy for Young BRCA Mutation Carriers at Risk of Pelvic Serous Carcinoma
Key Details
Gender
FEMALE
Age Range
35 Years - Any
Study Type
INTERVENTIONAL
Enrollment
123
Start Date
2012-01-09
Completion Date
2033-08
Last Updated
2026-03-18
Healthy Volunteers
No
Interventions
Radical fimbriectomy
Laparoscopic bilateral radical fimbriectomy : Complete resection of the tubes, from the uterine tube (up against the uterus) to the fimbriae, with resection of the part of the ovary adjacent to the ovarian fimbriae (adhering to the ovary)
Histopathology SEE-FIM
Anatomopathological study of surgical specimens
Locations (14)
Polyclinique du Parc Rambot
Aix-en-Provence, France
Institut Bergonié
Bordeaux, France
Centre Jean Perrin
Clermont-Ferrand, France
Centre Oscar Lambret
Lille, France
CHR-U
Lille, France
Clinique du Bois - Bourgogne Center
Lille, France
Hospices Civils de Lyon
Lyon, France
Institut Paoli Calmettes
Marseille, France
Centre Antoine Lacassagne
Nice, France
Institut Curie
Paris, France
Centre Henri Becquerel
Rouen, France
IUCT-O Toulouse
Toulouse, France
Institut Gustave Roussy
Villejuif, France
Hôpital Privé VA
Villeneuve-d'Ascq, France